[1]周地福,翟伟科,孙颖,等.结直肠恶性组织黏膜面与浆膜面、癌旁1、3 cm以及正常组织黏膜面与浆膜面的介电特性差异[J].南方医科大学学报,2018,(04):434.
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结直肠恶性组织黏膜面与浆膜面、癌旁1、3 cm以及正常组织黏膜面与浆膜面的介电特性差异()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2018年04期
页码:
434
栏目:
出版日期:
2018-04-30

文章信息/Info

Title:
Differences in dielectric properties between mucosal and serosal surface of malignant colorectal tissues, adjacent tissues at 1 cm and 3 cm and normal colorectal tissues
作者:
周地福翟伟科孙颖韩帅黄陆茂辛学刚厉周余学飞
关键词:
结直肠癌介电特性开端同轴探头癌旁组织
Keywords:
Colorectal cancer dielectric properties open-ended coaxial probe Paracancerous tissues
摘要:
目的研究结直肠的恶性组织黏膜面与浆膜面、癌旁1、3 cm以及正常组织黏膜面与浆膜面之间的介电特性(相对介电常数 和电导率)差异。方法采用开端同轴探头法在50 MHz~3 GHz频段上对39例结直肠癌患者的新鲜离体标本的恶性组织黏膜面 与浆膜面、癌旁1、3 cm以及正常组织黏膜面与浆膜面的介电特性分别进行测量,然后分别分析其对应的介电特性,并对其中6 个特定频率点的介电特性数据进行统计学检验。结果结果显示恶性组织黏膜面介电特性高于癌旁1、3 cm及正常组织黏膜面 的介电特性,并且在六个特定频率点处存在显著性差异(P<0.01);癌旁1、3 cm及正常组织黏膜面介电特性依次减小;此外恶性 组织黏膜面与黏膜面介电特性在64、128、298、433、915 Mhz存在差异(P<0.01),而在2450 MHz无差异(P>0.01);正常组织黏膜 面与浆膜面介电特性不存在显著性差异(P>0.01)。结论恶性组织,癌旁1、3 cm及正常组织的黏膜面介电特性依次减小。另 外,恶性组织黏膜面介电特性高于浆膜面,而正常组织黏膜面与浆膜面的介电特性无显著差异。
Abstract:
Objective To investigate the differences in dielectric properties (relative permittivity and conductivity) between the mucosal surface and serosal surface of malignant colorectal tissues, adjacent tissues at 1 cm and 3 cm from the tumor focus and normal colorectal tissues. Methods The dielectric properties of the mucosal and serosal surface of malignant colorectal tissues, adjacent tissues (1 cm and 3 cm) and normal colorectal tissues from 39 patients with colorectal cancer were measured with an open-ended coaxial probe within the frequency range of 50 MHz-3 GHz, and the corresponding dielectric properties were analyzed respectively; statistical tests of the data were used to analyze the dielectric properties at 6 specific frequency points. Results The dielectric properties were significantly higher in the malignant mucosa surface than in the adjacent tissues and normal colorectal tissues at the 6 specific frequency points (P<0.01). The dielectric properties decreased progressively in adjacent tissues at 1 cm and 3 cm and normal mucosa surface. The mucosal and serosal surface of malignant tissues showed significant differences in dielectric properties at 64 MHz, 128 MHz, 298 MHz, 433 MHz, and 915 MHz (P<0.01) but not at 2450 MHz (P>0.01), but such differences were not observed in normal tissues (P>0.01). Conclusion The dielectric properties of the mucosal surface of the mucosal decrease in the order of malignant colorectal tissue, adjacent tissues at 1 cm and 3 cm from the tumor foci and normal colorectal tissues. The dielectric properties are higher in the mucosal surface than in the serosal surface in the malignant tissue, but comparable in normal colorectal tissues.

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更新日期/Last Update: 1900-01-01